# Microsoft Defender Integration with Morphisec _Last updated: 2025-09-24_ Morphisec enhances Microsoft Defender for Endpoint by preventing unknown, zero-day, in-memory, and other advanced attacks through a Defense-in-Depth approach that reduces attack blast radius and lowers organizational cyber risk exposure. ## Overview Morphisec is a member of the Microsoft Intelligence Security Association (MISA) and is listed in the [Azure Marketplace](https://azuremarketplace.microsoft.com/en-us/marketplace/apps/morphisec.morphisec_threat_prevention?tab=Overview) and the [Microsoft App Store](https://appsource.microsoft.com/en-gb/product/web-apps/morphisec.morphisec_threat_prevention?tab=Overview). ## Problem: Limitations of Signature-Based Endpoint Detection and Response Sophisticated threats are capable of bypassing EDR solutions like Microsoft Defender for Endpoint. EDR is primarily signature-based, leaving organizations vulnerable to zero-days, unknown, and fileless attacks. Cybercriminals use increasingly evasive tactics to deploy ransomware and other malicious software that bypass traditional endpoint protection measures. ## Solution: Defense-in-Depth with Morphisec Morphisec enhances Microsoft Defender for Endpoint by preventing unknown, zero-day, in-memory, and other advanced attacks. Morphisec implements Defense-in-Depth, effectively reducing the blast radius of attacks and ensuring anti-ransomware protection. Morphisec integrates with Defender to allow viewing of blocked attacks directly in the Microsoft Defender for Endpoint security console and prioritizing alerts in the Active Alerts list. ## Key Capabilities ### Prevent Ransomware Powered by AMTD (Automated Threat Defense), Morphisec prevents sophisticated ransomware from bypassing Defender for Endpoint by stopping ransomware attacks at multiple stages. ### Enhance Operational Efficiency Seamless integration with Microsoft Defender for Endpoint, combined with early threat prevention and accurate threat classification, reduces time and costs associated with technical resources. ### Strengthen Security Posture Morphisec helps boost audit scores and achieve compliance, which can lead to reduced cyber insurance premiums and an optimized overall cybersecurity posture. ### Improve Resiliency Morphisec ensures that Microsoft Defender for Endpoint remains operational and effective, providing clear prioritization for remediating software vulnerabilities. ## Customer Testimonials **Principal Cybersecurity Architect, $5B USD company:** "We love Morphisec. We just had a pentest done and they could not beat Morphisec. They kept saying 'what are you guys running'? The pentester tried to exploit Defender but Morphisec just would not let it happen." **Billy Sainz, IT Operations Manager, Citizens Medical Center:** "Morphisec provides full visibility into security events for Microsoft Defender and Morphisec in one dashboard. In the single pane of glass provided by Morphisec, it's all right there at your fingertips: easy to access and easy to understand." **VP Information Security, $500–$1B Insurance company:** "Morphisec provides a different approach to endpoint security that is innovative and goes after stopping rather than just detecting malware and breaches. In the dashboard, we can see Morphisec defeat malware that was about to get through Microsoft Defender." **VP Information Technology, $50–250M Software company:** "I feel a lot better about the state of our endpoint security supplementing our MS Defender environment with Morphisec. It is capable of identifying suspicious behavior and taking appropriate action, rather than relying on a pre-set definition table." ## Case Study: Radwell **Company:** Radwell **Industry:** Industrial automation **Employees:** 2,000+ **Headquarters:** USA **Revenue:** $1.2B USD Radwell adopted Morphisec and Microsoft Defender for unified security. [Read the case study](https://engage.morphisec.com/hubfs/case-studies/CASE%20STUDY-Radwell-2021-02.pdf). ## Resources - [View Morphisec in action](https://www.morphisec.com/demo/) - [Get the whitepaper: Morphisec + Microsoft Defender for Endpoint](/morphisec-microsoft-defender-whitepaper/) - [EDR × Morphisec Datasheet](https://www.morphisec.com/wp-content/uploads/2025/01/EDR-x-Morphisec-Datasheet.jpg)